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Table 2 Proportions of TSAs across different tiers of reproducibility assessment

From: Lack of reproducibility of trial sequential analyses: a meta-epidemiological study

Tier

Reported information

Group

Proportion

First tier

Essential data for reproducing RIS

Group A (without information)

28% (27/98)

Group B (with information)

72% (71/98)

Second tier

Essential data for reproducing decision boundaries and Z-curves

Group C (without information)

28% (5/27)

Group D (with information)

72% (22/27)

Third tier

All essential data for reproducing TSAs

Group E (non-reproducible TSAs)

87% (85/98)

Group F (reproducible TSAs)

13% (13/98)